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I-ELCAP Publications

I-ELCAP Investigator Peer-reviewed Publications

• Shaham D, Yankelevitz DF, Vazquez M, Kramer A, Bogot N, Henschke CI. Assessment of CT features of intrapulmonary lymph nodes confirmed by cytology. Clinical Imaging 2010; 34:185-190
• Huang Y, Xu D, Jirapatnakul J, Reeves AP, Farooqi A, Zhang L, Giunta S, Zulueta J, Aye R, Miller A, Mendelson DS, Aylesworth C, Sheppard B, Klingler K, Yankelevitz DF, Henschke CI. CT and computer-based features of small hamartomas. Clinical Imaging 2010; In press
• Mulshine JL, Avila R, Yankelevitz D, Baer TM. Use of high-resolution CT imaging data in lung cancer drug development: measuring progress. Oncology (Williston Park). 2009; 30;23(5):434-8
• Zhang L, Yankelevitz DF, Henschke CI, Reeves AP, Vazquez MF, Carter D. Variation in vascular distribution in small lung cancers. Lung Cancer 2009; [Epub ahead of print] PubMed PMID: 19716621
• Lee J, Biancardi AM, Reeves AP, Yankelevitz DF, Henschke CI. Estimation of anatomical locations using standard frame of reference in chest CT scans. Conf Proc IEEE Eng Med Biol Soc. 2009:5809-12
• Anderson CM, Yip R, Henschke CI, Yankelevitz DF, Ostroff JS, Burns DM. Smoking cessation and relapse during a lung cancer screening program. Cancer Epidemiol Biomarkers Prev. 2009 18: 3476-83
• Wisnivesky JP, Henschke CI, Swanson S, Yankelevitz DF, Zulueta J, Marcus S, Halm EA. Limited resection for the treatment of patients with Stage IA lung cancer. Annuals of Surgery In press 2009
• Vazquez M, Carter D, Brambilla E, Gazdar A, Noguchi M, Travis W, Huang Y, Zhang L, Yip R, Yankelevitz DF, Henschke CI. Solitary and Multiple Resected Adenocarcinomas after CT Screening for Lung Cancer: Histopathologic Features and their Prognostic Implications. Lung Cancer 2009; 64:148-154
• Jirapatnakul AC, Fotin SV, Reeves AP, Biancardi AM, Yankelevitz DF, Henschke CI. Automated nodule location and size estimation using a multi-scale Laplacian of Gaussian filtering approach. Conf Proc IEEE Eng Med Biol Soc. 2009; Pgs 721-1078:1028-31
• Reeves AP, Biancardi AM, Yankelevitz D, Fotin S, Keller BM, Jirapatnakul A,Lee J. A public image database to support research in computer aided diagnosis. Conf Proc IEEE Eng Med Biol Soc. 2009:3715-8
• Yankelevitz DF. Screening for a cancer: acting on social responsibility. AJR Am J Roentgenol. 2007; 188(5):1171-2
• Henschke CI, Yankelevitz DF, Altorki NK. The role of CT screening for lung cancer. Thorac Surg Clin. 2007; 17(2):137-42
• Yankelevitz DF. Will the national lung screening trial be able to demonstrate a mortality reduction? Radiology 2008; 246(2):653; author reply 653-4
• Zudaire I, Lozano MD, Vazquez MF, Pajares MJ, Agorreta J, Pio R, Zulueta JJ, Yankelevitz DF, Henschke CI, Montuenga LM. Molecular characterization of small peripheral lung tumors based on the analysis of fine needle aspirates. Histopathol 2008; 23: 33-40
• Henschke CI. CT screening for lung cancer. Viewpoint. Nature Clinical Practice Oncology 2007; 4: 440-441
• International Early Lung Cancer Action Program Investigators. CT screening for lung cancer: individualizing the benefit of the screening. European Respiratory Journal 2007; 30: 843-847
• International Early Lung Cancer Action Program Investigators. Survival of Patients with Stage I Lung Cancer Detected on CT Screening. New England Journal of Medicine 2006; 355:1763-1771
• International Early Lung Cancer Action Program Investigators. Women's susceptibility to tobacco carcinogens and survival after diagnosis of lung cancer. JAMA 2006; 296:180-184
• The International Early Lung Cancer Action Program Investigators. CT Screening for Lung Cancer: The relationship of disease stage to tumor size. Archives of Internal Medicine 2006; 166: 321-325

NY-ELCAP Investigator Peer-reviewed Publications

• Shemesh J, Henschke CI, Shaham D, Yip R, Farooqi A, Cham M, McCauley DM, Chen M, Smith JP, Libby DM, Pasmantier MW, Yankelevitz DF. Ordinal scoring of coronary artery calcifications on low-dose CT scans of the chest predicts deaths from cardiovascular disease. Radiology 2010; In press
• Foy M, Yip R, Chen X, Kimmel M, Gorlova OY, Henschke CI. Modeling the mortality reduction due to CT screening for lung cancer. Cancer 2010; In press
• Henschke CI, Boffetta P, Gorlova OY, Yip R,Delancey J, Foy M. Assessment of Lung-cancer Mortality Reduction from CT Screening. Lung Cancer 2010; In press
• NY-ELCAP Investigators. CT Screening for Lung Cancer: Diagnostic Performance. Radiology 2007; 243:239-49
• Henschke CI, Lee I, Wu N, Farooqi A, Yankelevitz DF, Khan A, Altorki NK, ELCAP and NY-ELCAP Investigators. CT Screening for Lung Cancer: Prevalence and Incidence of Mediastinal Masses. Radiology 2006; 239:586-590
• Carter D, Vazquez M, Flieder DB, Brambilla E, Gazdar A, Noguchi M, Travis WD, Kramer A, Yip R, Yankelevitz DF, Henschke CI, ELCAP and NY-ELCAP Investigators. Comparison of pathologic findings of baseline and annual repeat cancers. Lung Cancer 2007; 56:193-199

ELCAP Investigator Publications

• Zhang L, Yankelevitz DF, Henschke CI, Reeves AP, Vazquez MF, Carter D. Variation in vascular distribution in small lung cancers. Lung Cancer 2010; 68:389-393
• Zhang L, Yankelevitz DF, Henschke CI, Jirapatnakul A, Reeves AP, Carter D. Zone of transition: a potential source of error in tumor volume estimation. Radiology 2010; In press
• Henschke CI, Miettinen OS, Yankelevitz DF, Libby D, Smith JP. Radiographic screening for cancer: New paradigm for its scientific basis. Clinical Imaging 1994; 18:16-20
• Henschke CI, McCauley DI, Yankelevitz DF, Naidich DP, McGuinness G, Miettinen OS, Libby D, Pasmantier M, Koizumi J, Altorki N, Smith JP. Early Lung Cancer Action Project: Overall Design and Findings From Baseline Screening. The Lancet 1999; 354:99-105
• Yankelevitz DF, Gupta R, Zhao B, Henschke CI. Repeat CT Scanning for Evaluation of Small Pulmonary Nodules. Radiology 1999;212:561-566
• Zhao B, Yankelevitz DF, Reeves A, Henschke CI. 2-D multi-criteria automatic segmentation of pulmonary nodules of helical CT images. Medical Physics 1999; 26:889-895
• Zhao B, Reeves A, Yankelevitz DF, Henschke CI. 3-D multi-criteria automatic segmentation of pulmonary nodules of helical CT images. Optical Engineering 1999; 38:1348-1347
• Zhao B, Kostis WJ, Reeves AP, Yankelevitz DF, Henschke CI. Consistent segmentation of repeat CT scans for growth assessment in pulmonary nodules. Proceedings of the SPIE, Medical Imaging 1999; 3661:1012-18
• Yankelevitz DF, Reeves AP, Kostis WJ, Zhao B, Henschke CI. Small pulmonary nodules: volumetrically determined growth rates based on CT evaluation. Radiology 2000; 217:251-256
• Henschke CI, Naidich DP, Yankelevitz DF, McGuinness G, McCauley DI, Smith JP, Libby D, Pasmantier M, Koizumi J, Flieder D, Vazquez M, Altorki N, Miettinen OS. Early Lung Cancer Action Project: Initial results of annual repeat screening. Cancer 2001; 92:153-159
• Henschke C, Yankelevitz DF, Smith JP, Miettinen OS. The Use of Spiral CT in Lung Cancer Screening. Chapter in Progress in Oncology 2002, (eds. VT DeVita, S Hellman, SA Rosenberg). Jones and Bartlett, Boston MA, 2002:90-101
• Gorlova OY, Kimmel M, Henschke C. Modeling of long-term screening for lung cancer. Cancer 2001;92: 1531-1540
• Ostroff J. Buckshee N, Mancuso CA, Yankelevitz DF, Henschke CI. Smoking Cessation: an unexpected benefit of screening CT for detection of early lung cancer. Preventive Medicine 2001; 33: 613-621
• OS Miettinen, Henschke CI. CT screening for lung cancer: coping with nihilistic recommendations. Radiology 2001: 221:598-599
• OS Miettinen, Henschke CI. Commentary on “CT screening for lung cancer: not ready for routine practice." Radiology 2001: 221:592-599
• Miettinen OS, Henschke CI, Pasmantier MW, Smith JP, Libby DM, Yankelevitz DF. Mammographic screening: No reliable supporting evidence? Lancet 2002; 359:404-5
• Miettinen OS, Henschke CI, Pasmantier MW, Smith JP, Libby DM, Yankelevitz DF. Mammographic screening: No reliable supporting evidence? www.Lancet.com Feb 2,2002
• Henschke CI, Yankelevitz DF, Smith JP, Miettinen OS. Screening for lung cancer: the Early Lung Cancer Action Approach. Cancer 2002; 35:143-148
• Henschke CI, Yankelevitz DF, Mirtcheva R, McGuinness G, McCauley D, Miettinen OS. CT screening for lung cancer: Frequency and significance of part-solid and nonsolid nodules. AJR 2002; 178:1053-1057.
• Yankelevitz DF, Kostis WF, Henschke CI, Heelan RT, Libby DM, Pasmantier MW, Smith JP. Overdiagnosis in chest radiographic screening for lung carcinoma: Frequency. Cancer 2003; 97:1271-5
• Henschke CI, Wisnivesky JP, Yankelevitz DF, Miettinen OS. Screen-diagnosed small Stage I cancers of the lung: Genuineness and Curability. Lung Cancer 2003; 39:327-30
• Vazquez M, Flieder D, Travis W, Carter D, Yankelevitz D, Miettinen OSM, Henschke CI. Early Lung Cancer Action Project Pathology Protocol. Lung Cancer 2003; 39:231-32
• Wisnivesky JP, Mushlin A, Sicherman N, Henschke CI. Cost effectivness of baseline low-dose CT screening for lung cancer: preliminary results. Chest 2003; 124: 614-621.
• Kostis WJ, Reeves AP, Yankelevitz DF, Henschke CI. Three-dimensional segmentation and growth-rate estimation of small pulmonary nodules in helical CT images. IEEE Transaction on Medical Imaging. 2003; 22:1259-1274
• Miettinen OS, Yankelevitz DF, Henschke CI.  Evaluation of screening for a cancer: annotated catechism of the Gold Standard creed. Journal of Evaluation in Clinical Practice 2003; 9:145-150
• Kostis WJ, Fluture SC, Farooqi AO, Yankelevitz DF, Henschke CI. Volumetric assessment of emphysema on low-dose screening CT scans. SPIE Medical Imaging 2003; 5032:827-834
• Kostis WJ, Fluture S, Yankelevitz DF, Henschke CI. Method for analysis and display of distribution of emphysema in CT scans. SPIE Medical Imaging 2003; 5032:199-206
• Henschke CI, Miettinen OS. Women’s susceptibility to tabacco carcinogens. Lung Cancer 2004: 43:1-5
• Henschke CI, Yankelevitz DF, Naidich DP, McCauley DI, McGuinness G, Libby DM, Smith JP, Pasmantier MW, Miettinen OS. CT screening for lung cancer: Suspiciousness of nodules according to size on baseline scans. Radiology 2004;231:164-8
• Kostis WJ, Yankelevitz DF, Reeves AP, Fluture SC, Henschke CI. Small pulmonary nodules: reproducibility of three-dimensional volumetric measurement and estimation of time to follow-up CT. Radiology 2004; 231:446-52
• Henschke CI, Yankelevitz DF, Smith JP, Libby D, Pasmantier MW, McCauley CI, McGuinness G, Naidich DP, Farooqi A, Vazquez M, Miettinen OS. CT Screening for Lung Cancer: Assessing a Regimen’s Diagnostic Performance. Clinical Imaging 2004; 28:317-321
• Wisnivesky JP, Yankelevitz DF, Henschke CI. The effect of tumor size on curability of Stage I non-small-cell lung cancers. Chest 2004; 126:761-765
• Yankelevitz DF, Wisnivesky JP, Henschke CI. Stage of lung cancer in relation to its size. 1. Insight. Chest 2005; 127: 1132-1135
• Wisnivesky JP, Yankelevitz DF, Henschke CI. Stage of lung cancer in relation to its size. 2. Evidence. Chest 2005; 127: 1136-1139
• Chapman B, Yankelevitz DF, Henschke CI, Gur D. Simulations of the effect of imperfect detection on the temporal dynamics of a lung cancer screening program. Radiology 2005; 234:582-590
• Kimmel M, Gorlova OY, Henschke CI. Modeling lung cancer screening. (Chapter 10 in Quantitative Methods for Cancer and Human Health Risk Assessment, eds: L. Edler and C. Kitsos), Wiley and Sons, England. 2005; Chapter 10:161-176
• Henschke CI, Shaham D, Yankelevitz DF, Carter D, Vazquez M, Kostis WJ, Reeves AP, Kramer A, Miettinen OS. CT Screening for Lung Cancer: Significance of diagnoses in the baseline cycle of screening. Clinical Imaging 2006; 30:11-15
• Libby D, Wu N., Lee I, Farooqi A, Henschke CI. CT Screening for Lung Cancer: the value of short-term CT follow-up. Chest 2006; 129:1039-1042
• Flieder DB, Vazquez M, Carter D, Brambilla E, Gazdar A, Noguchi M, Travis WD, Kramer A, Yankelevitz DF, Henschke CI and ELCAP Investigators. Pathologic findings of lung tumors diagnosed on baseline CT screening. American Journal of Surgical Pathology 2006; 30:606-613
• Reeves A, Chan A, Yankelevitz D, Henschke C, Kessler B, Kostis WJ.  On measuring the change in size of pulmonary nodules. IEEE Transactions on Medical Imaging 2006;25:433-450
• Shemesh J, Henschke CI, Farooqi A, Yip R, Yankelevitz DF, Shaham D, Miettinen OS. Frequency of Coronary Artery calcification on Low-dose Computed Tomography Screening for Lung Cancer. Clinical Imaging 2006; 30:181-185
• Henschke CI, Yip R, Yankelevitz DF, Miettinen OS. CT screening for lung cancer: competing causes of death. Clinical Lung Cancer 2006; 7:323-325
• Wisnivesky JP, Henschke CI, Yankelevitz DF. Diagnostic percutaneous transthoracic needle biopsy does not affect survival of Stage I lung cancer. American Journal of Respiratory and Critical Care Medicine. 2006; 170: 684-688
• Henschke CI, Smith JP, Miettinen OS. Answers to letters. New England Journal of Medicine 2007; 356:743-747

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